翻訳と辞書 Words near each other ・ Materikaa ・ Materine užance ・ Materiomics ・ Materlândia ・ Materna (disambiguation) ・ Materna coat of arms ・ Maternal and Child Health (MCH) Library ・ Maternal and Child Health Bureau ・ Maternal and child health in Tanzania ・ Maternal and Newborn Health in Ethiopia Partnership – MaNHEP ・ Maternal autoimmune bullous disease ・ Maternal bond ・ Maternal death ・ Maternal deprivation ・ Maternal effect ・ Maternal effect dominant embryonic arrest ・ Maternal feminism ・ Maternal health ・ Maternal health in Angola ・ Maternal health in Ethiopia ・ Maternal health in Rwanda ・ Maternal health in Uganda ・ Maternal Health Task Force ・ Maternal hypothyroidism ・ Maternal impression ・ Maternal instinct ・ Maternal insult ・ Maternal mortality in fiction ・ Maternal near miss ・ Maternal physiological changes in pregnancy Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Maternal effect dominant embryonic arrest ： ウィキペディア英語版 Maternal effect dominant embryonic arrest __NOTOC__ Maternal effect dominant embryonic arrest (Medea) is a selfish gene composed of a toxin and an antidote. A mother carrying ''Medea'' will express the toxin in her germline, killing her progeny. If the children also carry ''Medea'', they produce copies of the antidote, saving their lives. Therefore, if a mother has one ''Medea'' allele and one non-Medea allele, half of her children will inherit ''Medea'' and survive while the other half will inherit the non-Medea allele and die (unless they receive ''Medea'' from their father). Medea's selfish behavior gives it a selective advantage over normal genes. If introduced into a population at sufficiently high levels, the ''Medea'' gene will spread, replacing entire populations of normal beetles with beetles carrying ''Medea''.〔Wade, M.J. and Beeman, R.W. (1994) The Population Dynamics of Maternal-Effect Selfish Genes. Genetics 138: 1309-1314.〕 Because of this, ''Medea'' has been proposed as a way of genetically modifying insect populations. By linking the ''Medea'' construct to a gene of interest - for instance, a gene conferring resistance to malaria - ''Medeas unique dynamics could be exploited to drive both genes into a population. These findings have dramatic implications for the control of insect-borne diseases such as malaria and dengue fever. == Construction of Medea == Medea, which has been found in nature only in flour beetles, is the only selfish gene that has been simulated in the lab and tested in the fruit fly ''Drosophila melanogaster''. The toxin was a microRNA that blocked the expression of ''myd88'', a gene vital for embryonic development in insects. The antidote was an extra copy of ''myd88''. The offspring receiving the extra copy of ''myd88'' survived and hatched, while those without the extra copy died. In lab trials where 25% of the original members were homozygous for ''Medea'', the gene spread to the entire population within 10 to 12 generations.〔Chen, C-H. et al. (2007) A Synthetic Maternal-Effect Selfish Genetic Element Drives Population Replacement In Drosophila. ''Science'': 316(5824):597-600. () 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Maternal effect dominant embryonic arrest」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.